National Centre for Biological Sciences

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The mandate of NCBS is basic research in the frontier areas of biology. The research interests of the faculty are in the following areas.

1) Biochemistry, Biophysics and Bioinformatics

2) Genetics and Development

3) Cellular Organization and Signaling

4) Neurobiology

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National Centre for Biological Sciences's Articles

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An evaluation of the PCR-RFLP technique to aid molecular-based monitoring of felids and canids in India

Authors: Shomita Mukherjee, Ashalakshmi CN, Chandrima Home and Uma Ramakrishnan

Citation: BMC Research Notes 2010 3:159

Content type: Short Report Published on: 7 June 2010
Systematic search for putative new domain families in Mycoplasma gallisepticum genome

Authors: Chilamakuri CS Reddy, Sane Sudha Rani, Bernard Offmann and R Sowdhamini

Citation: BMC Research Notes 2010 3:98

Content type: Short Report Published on: 12 April 2010
HORI: a web server to compute Higher Order Residue Interactions in protein structures

Authors: Pandurangan Sundaramurthy, Khader Shameer, Raashi Sreenivasan, Sunita Gakkhar and Ramanathan Sowdhamini

Citation: BMC Bioinformatics 2010 11(Suppl 1):S24

Content type: Research Published on: 18 January 2010

This article is part of a Supplement: Volume 11 Supplement 1
Cooperation of Notch and Ras/MAPK signaling pathways in human breast carcinogenesis

Authors: Suruchi Mittal, Deepa Subramanyam, Devaveena Dey, Rekha V Kumar and Annapoorni Rangarajan

Citation: Molecular Cancer 2009 8:128

Content type: Research Published on: 23 December 2009
Evaluating epistatic interaction signals in complex traits using quantitative traits

Authors: Odity Mukherjee, Krishna Rao Sanapala, Padmanabhan Anbazhagana and Saurabh Ghosh

Citation: BMC Proceedings 2009 3(Suppl 7):S82

Content type: Proceedings Published on: 15 December 2009

This article is part of a Supplement: Volume 3 Supplement 7
A panel of microsatellites to individually identify leopards and its application to leopard monitoring in human dominated landscapes

Authors: Samrat Mondol, Navya R, Vidya Athreya, Kartik Sunagar, Velu Mani Selvaraj and Uma Ramakrishnan

Citation: BMC Genetics 2009 10:79

Content type: Methodology article Published on: 4 December 2009
3PFDB - A database of Best Representative PSSM Profiles (BRPs) of Protein Families generated using a novel data mining approach

Authors: Khader Shameer, Paramasivam Nagarajan, Kumar Gaurav and Ramanathan Sowdhamini

Citation: BioData Mining 2009 2:8

Content type: Research Published on: 4 December 2009
Multiscale modeling and interoperability in MOOSE

Authors: Niraj Dudani, Subhasis Ray, Siji George and Upinder S Bhalla

Citation: BMC Neuroscience 2009 10(Suppl 1):P54

Content type: Poster presentation Published on: 13 July 2009

This article is part of a Supplement: Volume 10 Supplement 1
Analysis on conservation of disulphide bonds and their structural features in homologous protein domain families

Authors: Ratna R Thangudu, Malini Manoharan, N Srinivasan, Frédéric Cadet, R Sowdhamini and Bernard Offmann

Citation: BMC Structural Biology 2008 8:55

Content type: Research article Published on: 26 December 2008
Genome-wide survey of prokaryotic serine proteases: Analysis of distribution and domain architectures of five serine protease families in prokaryotes

Authors: Lokesh P Tripathi and R Sowdhamini

Citation: BMC Genomics 2008 9:549

Content type: Research article Published on: 19 November 2008
A general biological simulator: the multiscale object oriented simulation environment, MOOSE

Authors: Subhasis Ray, Raamesh Deshpande, Niraj Dudani and Upinder S Bhalla

Citation: BMC Neuroscience 2008 9(Suppl 1):P93

Content type: Poster presentation Published on: 11 July 2008

This article is part of a Supplement: Volume 9 Supplement 1
Large-scale synapse-level neuronal wiring diagrams in silico and in vitro

Authors: Upinder S Bhalla, Radhika Madhavan, Ashesh Dhawale, Mehrab Modi, Raamesh Deshpande, Niraj Dudani and Subhasis Ray

Citation: BMC Neuroscience 2008 9(Suppl 1):P20

Content type: Poster presentation Published on: 11 July 2008

This article is part of a Supplement: Volume 9 Supplement 1
Modules in molecular memory

Authors: Upinder S Bhalla

Citation: BMC Neuroscience 2008 9(Suppl 1):L2

Content type: Lecture presentation Published on: 11 July 2008

This article is part of a Supplement: Volume 9 Supplement 1
PURE: A webserver for the prediction of domains in unassigned regions in proteins

Authors: Chilamakuri CS Reddy, Khader Shameer, Bernard O Offmann and Ramanathan Sowdhamini

Citation: BMC Bioinformatics 2008 9:281

Content type: Research article Published on: 14 June 2008
CUSP: an algorithm to distinguish structurally conserved and unconserved regions in protein domain alignments and its application in the study of large length variations

Authors: Sankaran Sandhya, Barah Pankaj, Madabosse Kande Govind, Bernard Offmann, Narayanaswamy Srinivasan and Ramanathan Sowdhamini

Citation: BMC Structural Biology 2008 8:28

Content type: Research article Published on: 31 May 2008
A machine learning approach for the identification of odorant binding proteins from sequence-derived properties

Authors: Ganesan Pugalenthi, Ke Tang, PN Suganthan, G Archunan and R Sowdhamini

Citation: BMC Bioinformatics 2007 8:351

Content type: Research article Published on: 19 September 2007
The N-terminus and alpha-5, alpha-6 helices of the pro-apoptotic protein Bax, modulate functional interactions with the anti-apoptotic protein Bcl-x_L

Authors: Neha Parikh, Caroline Koshy, Vaigundan Dhayabaran, Lakshmi R Perumalsamy, R Sowdhamini and Apurva Sarin

Citation: BMC Cell Biology 2007 8:16

Content type: Research article Published on: 23 May 2007
Cross genome comparisons of serine proteases in Arabidopsis and rice

Authors: Lokesh P Tripathi and R Sowdhamini

Citation: BMC Genomics 2006 7:200

Content type: Research article Published on: 9 August 2006
Cross genome phylogenetic analysis of human and Drosophila G protein-coupled receptors: application to functional annotation of orphan receptors

Authors: Raghu Prasad Rao Metpally and Ramanathan Sowdhamini

Citation: BMC Genomics 2005 6:106

Content type: Research article Published on: 10 August 2005
Genome wide survey of G protein-coupled receptors in Tetraodon nigroviridis

Authors: Raghu Prasad Rao Metpally and Ramanathan Sowdhamini

Citation: BMC Evolutionary Biology 2005 5:41

Content type: Research article Published on: 15 July 2005

National Centre for Biological Sciences

National Centre for Biological Sciences's Articles

An evaluation of the PCR-RFLP technique to aid molecular-based monitoring of felids and canids in India

Systematic search for putative new domain families in Mycoplasma gallisepticum genome

HORI: a web server to compute Higher Order Residue Interactions in protein structures

Cooperation of Notch and Ras/MAPK signaling pathways in human breast carcinogenesis

Evaluating epistatic interaction signals in complex traits using quantitative traits

A panel of microsatellites to individually identify leopards and its application to leopard monitoring in human dominated landscapes

3PFDB - A database of Best Representative PSSM Profiles (BRPs) of Protein Families generated using a novel data mining approach

Multiscale modeling and interoperability in MOOSE

Analysis on conservation of disulphide bonds and their structural features in homologous protein domain families

Genome-wide survey of prokaryotic serine proteases: Analysis of distribution and domain architectures of five serine protease families in prokaryotes

A general biological simulator: the multiscale object oriented simulation environment, MOOSE

Large-scale synapse-level neuronal wiring diagrams in silico and in vitro

Modules in molecular memory

PURE: A webserver for the prediction of domains in unassigned regions in proteins

CUSP: an algorithm to distinguish structurally conserved and unconserved regions in protein domain alignments and its application in the study of large length variations

A machine learning approach for the identification of odorant binding proteins from sequence-derived properties

The N-terminus and alpha-5, alpha-6 helices of the pro-apoptotic protein Bax, modulate functional interactions with the anti-apoptotic protein Bcl-x_L

Cross genome comparisons of serine proteases in Arabidopsis and rice

Cross genome phylogenetic analysis of human and Drosophila G protein-coupled receptors: application to functional annotation of orphan receptors

Genome wide survey of G protein-coupled receptors in Tetraodon nigroviridis