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Genome-wide CRISPR guide RNA design and specificity analysis with GuideScan2

Authors: Henri Schmidt, Minsi Zhang, Dimitar Chakarov, Vineet Bansal, Haralambos Mourelatos, Francisco J. Sánchez-Rivera, Scott W. Lowe, Andrea Ventura, Christina S. Leslie and Yuri Pritykin

Citation: Genome Biology 2025 26:41

Content type: Methodology Published on: 26 February 2025
A refined analysis of Neanderthal-introgressed sequences in modern humans with a complete reference genome

Authors: Shen-Ao Liang, Tianxin Ren, Jiayu Zhang, Jiahui He, Xuankai Wang, Xinrui Jiang, Yuan He, Rajiv C. McCoy, Qiaomei Fu, Joshua M. Akey, Yafei Mao and Lu Chen

Citation: Genome Biology 2025 26:32

Content type: Research Published on: 17 February 2025
TAD-SIE: sample size estimation for clinical randomized controlled trials using a Trend-Adaptive Design with a Synthetic-Intervention-Based Estimator

Authors: Sayeri Lala and Niraj K. Jha

Citation: Trials 2025 26:31

Content type: Methodology Published on: 29 January 2025
Ethnobiology! Until when will the colonialist legacy be reinforced?

Authors: Sofia Zank, Cristiane Gomes Julião, Adriana de Souza de Lima, Marciano Toledo da Silva, Carolina Levis, Natalia Hanazaki and Nivaldo Peroni

Citation: Journal of Ethnobiology and Ethnomedicine 2025 21:1

Content type: Debate Published on: 10 January 2025
Changes in muscle performance among older adults with myeloid malignancies engaging in a mobile health (mHealth) exercise intervention: a single arm pilot study

Authors: Marielle Jensen-Battaglia, Po-Ju Lin, Chandrika Sanapala, Erin E. Watson, Jason H. Mendler, Jane Liesveld, Ying Wang, Elisabeth Hayward, Marissa LoCastro, Soroush Mortaz, Richard F. Dunne, Karen Mustian and Kah Poh Loh

Citation: BMC Geriatrics 2025 25:22

Content type: Research Published on: 9 January 2025
Anticipated facilitators and barriers for long-acting injectable antiretrovirals as HIV treatment and prevention in Vietnam: a qualitative study among healthcare workers

Authors: My T. Dang, Yen N. Le, Sarah Naz-McLean, Nhung T. T. Vo, Phuong T. Do, Linh T. T. Doan, Nhan T. Do, Mai T. Nguyen, An H. Phan, Eric J. Dziuban, Ramona Bhatia, Lisa Cosimi, Huong T. T. Phan and Todd M. Pollack

Citation: BMC Infectious Diseases 2024 24:1462

Content type: Research Published on: 25 December 2024
Loss of mitochondrial enzyme GPT2 leads to reprogramming of synaptic glutamate metabolism

Authors: Ozan Baytas, Shawn M. Davidson, Julie A. Kauer and Eric M. Morrow

Citation: Molecular Brain 2024 17:87

Content type: Research Published on: 27 November 2024
Bayesian tip-dated timeline for diversification and major biogeographic events in Muroidea (Rodentia), the largest mammalian radiation

Authors: Raquel López-Antoñanzas, Tiago R. Simões, Fabien L. Condamine, Moritz Dirnberger and Pablo Peláez-Campomanes

Citation: BMC Biology 2024 22:270

Content type: Research article Published on: 25 November 2024
Removal of sequencing adapter contamination improves microbial genome databases

Authors: Andrew H. Moeller, Brian A. Dillard, Samantha L. Goldman, Madalena V. F. Real and Daniel D. Sprockett

Citation: BMC Genomics 2024 25:1033

Content type: Research Published on: 4 November 2024
Discovering a “sense of community”: patient experiences of connection in intentionally remote eating disorder care

Authors: Hannah Wolfe, Caitlin B. Shepherd, Rebecca G. Boswell, Jessica Genet and Wendy Oliver-Pyatt

Citation: Journal of Eating Disorders 2024 12:171

Content type: Research Published on: 30 October 2024
Data-driven discovery of chemotactic migration of bacteria via coordinate-invariant machine learning

Authors: Yorgos M. Psarellis, Seungjoon Lee, Tapomoy Bhattacharjee, Sujit S. Datta, Juan M. Bello-Rivas and Ioannis G. Kevrekidis

Citation: BMC Bioinformatics 2024 25:337

Content type: Research Published on: 24 October 2024
Brief report: incidence and outcomes of pediatric tracheal intubation-associated cardiac arrests in the ICU-RESUS clinical trial

Authors: Akira Nishisaki, Ron W. Reeder, Elizabeth Laverriere McGovern, Tageldin Ahmed, Michael J. Bell, Robert Bishop, Matthew Bochkoris, Candice Burns, Joseph A. Carcillo, Todd C. Carpenter, Wesley Diddle, Myke Federman, Ericka L. Fink, Deborah Franzon, Aisha H. Frazier, Stuart H. Friess…

Citation: Critical Care 2024 28:286

Content type: Research Published on: 30 August 2024
Canine hyper-sociability structural variants associated with altered three-dimensional chromatin state

Authors: Dhriti Tandon, Enikő Kubinyi, Sára Sándor, Hannah Faughnan, Ádám Miklósi and Bridgett M. vonHoldt

Citation: BMC Genomics 2024 25:767

Content type: Research Published on: 7 August 2024
Clusters of long COVID among patients hospitalized for COVID-19 in New York City

Authors: Sara Venkatraman, Jesus Maria Gomez Salinero, Adina Scheinfeld, Sean Houghton, David Redmond, Monika Safford and Mangala Rajan

Citation: BMC Public Health 2024 24:1994

Content type: Research Published on: 25 July 2024
Early bolus epinephrine administration during pediatric cardiopulmonary resuscitation for bradycardia with poor perfusion: an ICU-resuscitation study

Authors: Amanda J. O’Halloran, Ron W. Reeder, Robert A. Berg, Tageldin Ahmed, Michael J. Bell, Robert Bishop, Matthew Bochkoris, Candice Burns, Joseph A. Carcillo, Todd C. Carpenter, J. Michael Dean, J. Wesley Diddle, Myke Federman, Richard Fernandez, Ericka L. Fink, Deborah Franzon…

Citation: Critical Care 2024 28:242

Content type: Research Published on: 16 July 2024
HATCHet2: clone- and haplotype-specific copy number inference from bulk tumor sequencing data

Authors: Matthew A. Myers, Brian J. Arnold, Vineet Bansal, Metin Balaban, Katelyn M. Mullen, Simone Zaccaria and Benjamin J. Raphael

Citation: Genome Biology 2024 25:130

Content type: Method Published on: 21 May 2024
Examining provider practice-level disparities in delivery outcomes among patients with a history of Cesarean Delivery

Authors: Lily McCarthy, Nicola F Tavella, Sara Wetzler, Lily Ardente, Molly Chadwick, Dexter Paul, Nikki Sabet, Toni Stern and Angela Bianco

Citation: BMC Pregnancy and Childbirth 2024 24:243

Content type: Research Published on: 5 April 2024
The chromosome-scale genome assembly for the West Nile vector Culex quinquefasciatus uncovers patterns of genome evolution in mosquitoes

Authors: Sergei S. Ryazansky, Chujia Chen, Mark Potters, Anastasia N. Naumenko, Varvara Lukyanchikova, Reem A. Masri, Ilya I. Brusentsov, Dmitriy A. Karagodin, Andrey A. Yurchenko, Vitor L. dos Anjos, Yuki Haba, Noah H. Rose, Jinna Hoffman, Rong Guo, Theresa Menna, Melissa Kelley…

Citation: BMC Biology 2024 22:16

Content type: Research article Published on: 25 January 2024
Chromatin activity identifies differential gene regulation across human ancestries

Authors: Kade P. Pettie, Maxwell Mumbach, Amanda J. Lea, Julien Ayroles, Howard Y. Chang, Maya Kasowski and Hunter B. Fraser

Citation: Genome Biology 2024 25:21

Content type: Research Published on: 15 January 2024
Natural killer cells drive 4-1BBL positive uveal melanoma towards EMT and metastatic disease

Authors: Shi Yong Neo, Mariana M. S. Oliveira, Le Tong, Yi Chen, Ziqing Chen, Sonia Cismas, Nutsa Burduli, Anna Malmerfelt, Joey Kay Hui Teo, Kong-Peng Lam, Evren Alici, Leonard Girnita, Arnika K. Wagner, Lisa S. Westerberg and Andreas Lundqvist

Citation: Journal of Experimental & Clinical Cancer Research 2024 43:13

Content type: Research Published on: 9 January 2024