Group Research & Development Centre - British American Tobacco

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Group Research & Development Centre is based in the UK. Our 300 scientists undertake research in a broad spectrum of scientific fields including molecular biology, toxicology, analytical smoke chemistry and tobacco biotechnology. Our current research focuses on developing less harmful tobacco products and the science needed to assess them and considers both combustible product and smokeless tobacco.

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Group Research & Development Centre - British American Tobacco's Articles

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Modelling the nicotine pharmacokinetic profile for e-cigarettes using real time monitoring of consumers’ physiological measurements and mouth level exposure

Authors: Krishna Prasad, Allen Griffiths, Kavya Agrawal, Michael McEwan, Flavio Macci, Marco Ghisoni, Matthew Stopher, Matthew Napleton, Joel Strickland, David Keating, Thomas Whitehead, Gareth Conduit, Stacey Murray and Lauren Edward

Citation: BioData Mining 2024 17:24

Content type: Research Published on: 17 July 2024
An exploratory, randomised, crossover study to investigate the effect of nicotine on cognitive function in healthy adult smokers who use an electronic cigarette after a period of smoking abstinence

Authors: Harry J. Green, Olivia K. O’Shea, Jack Cotter, Helen L. Philpott and Nik Newland

Citation: Harm Reduction Journal 2024 21:78

Content type: Research Published on: 6 April 2024
In vitro biological assessment of the stability of cigarette smoke aqueous aerosol extracts

Authors: Mark Taylor, Simone Santopietro, Andrew Baxter, Nicole East, Damien Breheny, David Thorne and Marianna Gaça

Citation: BMC Research Notes 2020 13:492

Content type: Research note Published on: 21 October 2020
Results from a 2018 cross-sectional survey in Tokyo, Osaka and Sendai to assess tobacco and nicotine product usage after the introduction of heated tobacco products (HTPs) in Japan

Authors: Jason Adamson, Claudia Kanitscheider, Krishna Prasad, Oscar M. Camacho, Elisabeth Beyerlein, Yoga Keralapura Bhagavan, Christopher Proctor and James Murphy

Citation: Harm Reduction Journal 2020 17:32

Content type: Research Published on: 26 May 2020
Evaluation of an online, real-time, soft-photon ionisation time-of-flight mass spectrometer for mainstream tobacco smoke analysis

Authors: Jenni Hawke, Graham Errington and Matthias Bente von Frowein

Citation: BMC Chemistry 2019 13:135

Content type: Research article Published on: 21 December 2019
The composition of contemporary American and Swedish smokeless tobacco products

Authors: Kevin G. McAdam, Harriet Kimpton, Arif Faizi, Andrew Porter and Brad Rodu

Citation: BMC Chemistry 2019 13:31

Content type: Research article Published on: 19 March 2019
Analysis of coumarin and angelica lactones in smokeless tobacco products

Authors: Kevin McAdam, Trevor Enos, Carol Goss, Harriet Kimpton, Arif Faizi, Steve Edwards, Christopher Wright, Andrew Porter and Brad Rodu

Citation: Chemistry Central Journal 2018 12:142

Content type: Research Article Published on: 20 December 2018
Ethyl carbamate in Swedish and American smokeless tobacco products and some factors affecting its concentration

Authors: K. McAdam, C. Vas, H. Kimpton, A. Faizi, C. Liu, A. Porter, T. Synnerdahl, P. Karlsson and B. Rodu

Citation: Chemistry Central Journal 2018 12:86

Content type: Research Article Published on: 24 July 2018
Optimized method for determination of 16 FDA polycyclic aromatic hydrocarbons (PAHs) in mainstream cigarette smoke by gas chromatography–mass spectrometry

Authors: Jana Jeffery, Maria Carradus, Karolina Songin, Michael Pettit, Karl Pettit and Christopher Wright

Citation: Chemistry Central Journal 2018 12:27

Content type: Research article Published on: 13 March 2018
Comprehensive survey of radionuclides in contemporary smokeless tobacco products

Authors: K. McAdam, H. Kimpton, A. Porter, C. Liu, A. Faizi, M. Mola, J. McAughey and B. Rodu

Citation: Chemistry Central Journal 2017 11:131

Content type: Research Article Published on: 19 December 2017
A randomised, controlled, two-Centre open-label study in healthy Japanese subjects to evaluate the effect on biomarkers of exposure of switching from a conventional cigarette to a tobacco heating product

Authors: Nathan Gale, Mike McEwan, Alison C. Eldridge, Neil Sherwood, Edward Bowen, Simon McDermott, Emma Holmes, Andrew Hedge, Stuart Hossack, Oscar M. Camacho, Graham Errington, John McAughey, James Murphy, Chuan Liu, Christopher J. Proctor and Ian M. Fearon

Citation: BMC Public Health 2017 17:673

Content type: Study protocol Published on: 22 August 2017
A reference genome for Nicotiana tabacum enables map-based cloning of homeologous loci implicated in nitrogen utilization efficiency

Authors: K. D. Edwards, N. Fernandez-Pozo, K. Drake-Stowe, M. Humphry, A. D. Evans, A. Bombarely, F. Allen, R. Hurst, B. White, S. P. Kernodle, J. R. Bromley, J. P. Sanchez-Tamburrino, R. S. Lewis and L. A. Mueller

Citation: BMC Genomics 2017 18:448

Content type: Research article Published on: 19 June 2017
Application of dosimetry tools for the assessment of e-cigarette aerosol and cigarette smoke generated on two different in vitro exposure systems

Authors: Jason Adamson, David Thorne, Benjamin Zainuddin, Andrew Baxter, John McAughey and Marianna Gaça

Citation: Chemistry Central Journal 2016 10:74

Content type: Research article Published on: 9 December 2016
The acrylamide content of smokeless tobacco products

Authors: Kevin McAdam, Harriet Kimpton, Carl Vas, David Rushforth, Andrew Porter and Brad Rodu

Citation: Chemistry Central Journal 2015 9:56

Content type: Research article Published on: 12 October 2015
An experimental method to study emissions from heated tobacco between 100-200°C

Authors: Mark Forster, Chuan Liu, Martin G Duke, Kevin G McAdam and Christopher J Proctor

Citation: Chemistry Central Journal 2015 9:20

Content type: Research article Published on: 16 April 2015
Analysis of hydrazine in smokeless tobacco products by gas chromatography–mass spectrometry

Authors: Kevin McAdam, Harriet Kimpton, Sofia Essen, Peter Davis, Carl Vas, Christopher Wright, Andrew Porter and Brad Rodu

Citation: Chemistry Central Journal 2015 9:13

Content type: Research article Published on: 16 March 2015
Characterisation of an aerosol exposure system to evaluate the genotoxicity of whole mainstream cigarette smoke using the in vitro γH2AX assay by high content screening

Authors: Carolina Garcia-Canton, Graham Errington, Arturo Anadon and Clive Meredith

Citation: BMC Pharmacology and Toxicology 2014 15:41

Content type: Research article Published on: 23 July 2014
Development of a BALB/c 3T3 neutral red uptake cytotoxicity test using a mainstream cigarette smoke exposure system

Authors: David Thorne, Joanne Kilford, Rebecca Payne, Linsey Haswell, Annette Dalrymple, Clive Meredith and Deborah Dillon

Citation: BMC Research Notes 2014 7:367

Content type: Short Report Published on: 17 June 2014
Longitudinal study of long-term smoking behaviour by biomarker-supported determination of exposure to smoke

Authors: Anthony Cunningham, Johan Sommarström, Ajit S Sisodiya, Graham Errington and Krishna Prasad

Citation: BMC Public Health 2014 14:348

Content type: Study protocol Published on: 12 April 2014
A novel autoantibody test for the detection of pre-neoplastic lung lesions

Authors: Frazer J Lowe, Weike Shen, Jinchi Zu, Junfu Li, Hao Wang, Xufei Zhang and Li Zhong

Citation: Molecular Cancer 2014 13:78

Content type: Research Published on: 5 April 2014

Group Research & Development Centre - British American Tobacco

Group Research & Development Centre - British American Tobacco's Articles

Modelling the nicotine pharmacokinetic profile for e-cigarettes using real time monitoring of consumers’ physiological measurements and mouth level exposure

An exploratory, randomised, crossover study to investigate the effect of nicotine on cognitive function in healthy adult smokers who use an electronic cigarette after a period of smoking abstinence

In vitro biological assessment of the stability of cigarette smoke aqueous aerosol extracts

Results from a 2018 cross-sectional survey in Tokyo, Osaka and Sendai to assess tobacco and nicotine product usage after the introduction of heated tobacco products (HTPs) in Japan

Evaluation of an online, real-time, soft-photon ionisation time-of-flight mass spectrometer for mainstream tobacco smoke analysis

The composition of contemporary American and Swedish smokeless tobacco products

Analysis of coumarin and angelica lactones in smokeless tobacco products

Ethyl carbamate in Swedish and American smokeless tobacco products and some factors affecting its concentration

Optimized method for determination of 16 FDA polycyclic aromatic hydrocarbons (PAHs) in mainstream cigarette smoke by gas chromatography–mass spectrometry

Comprehensive survey of radionuclides in contemporary smokeless tobacco products

A randomised, controlled, two-Centre open-label study in healthy Japanese subjects to evaluate the effect on biomarkers of exposure of switching from a conventional cigarette to a tobacco heating product

A reference genome for Nicotiana tabacum enables map-based cloning of homeologous loci implicated in nitrogen utilization efficiency

Application of dosimetry tools for the assessment of e-cigarette aerosol and cigarette smoke generated on two different in vitro exposure systems

The acrylamide content of smokeless tobacco products

An experimental method to study emissions from heated tobacco between 100-200°C

Analysis of hydrazine in smokeless tobacco products by gas chromatography–mass spectrometry

Characterisation of an aerosol exposure system to evaluate the genotoxicity of whole mainstream cigarette smoke using the in vitro γH2AX assay by high content screening

Development of a BALB/c 3T3 neutral red uptake cytotoxicity test using a mainstream cigarette smoke exposure system

Longitudinal study of long-term smoking behaviour by biomarker-supported determination of exposure to smoke

A novel autoantibody test for the detection of pre-neoplastic lung lesions