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Call for papers - Mitochondrial metabolism and dynamics

Guest Editors

Valentina Perissi, PhD, Boston University, USA
Ulrike Topf, PhD, Polish Academy of Sciences, Poland
Hong Xu, PhD, National Institute of Health, USA
Mara Zilocchi, PhD, University of Milano-Bicocca, Milano, Italy

Submission Status: Open   |   Submission Deadline: 10 October 2025

BMC Biology is calling for submissions to our Collection on Mitochondrial metabolism and dynamics. This Collection aims to explore the molecular mechanisms underlying mitochondrial function, mitochondrial dynamics, and their involvement in metabolic diseases, neurodegenerative disorders, and cancer. We further invite submissions that provide insights into potential therapeutic targets and interventions for diseases associated with mitochondrial dysfunction. We also welcome research seeking to understand the function of mitochondria in plants and their role in physiological and adaptive responses to biotic and abiotic stress.

New Content ItemThis Collection supports and amplifies research related to SDG 3: Good Health and Well-Being and SDG 15: Life on Land.

Meet the Guest Editors

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Valentina Perissi, PhD, Boston University, USA

Dr Valentina Perissi earned her BSc and MSc (“Laurea”) in Molecular Biology from the University of Torino, Italy, and a PhD in Molecular Pathology from UCSD, where she studied transcriptional regulation and chromatin remodeling. She completed postdoctoral training in Endocrinology and Metabolism under Dr M. Geoff Rosenfeld at UCSD. Now an Associate Professor of Biochemistry and Cell Biology at Boston University, Dr Perissi’s research focuses on genomic regulation of metabolism, emphasizing mitochondria-nuclear communication. 

Ulrike Topf, PhD, Polish Academy of Sciences, Poland

Dr Ulrike Topf received her PhD in 2011 from the Friedrich Miescher Institute/ University of Basel, Switzerland. She completed her postdoctoral training at the International Institute of Molecular and Cell Biology in Warsaw (IIMCB), Poland, where she contributed to the discovery of cellular responses to mitochondrial stress caused by impairment of protein import into mitochondria. In 2018, Dr Topf became an Assistant Professor and Research Group Leader. Her group studies cellular mechanisms that modulate mitochondrial function during acute cellular stress and ageing in yeast and C. elegans, with the long-term goal of identifying molecular targets to improve an organism's healthspan.

Hong Xu, PhD, National Institute of Health, USA

Dr Hong Xu earned his BSc from Nankai University and MSc from Peking University in China. In 1998, he moved to the United States to pursue a PhD at the Johns Hopkins University School of Medicine, studying Drosophila visual transduction. From 2005-2009, Dr Xu conducted postdoctoral research at the University of California, San Francisco, where he developed a method for selecting inheritable mtDNA mutations in Drosophila, laying the foundation for future studies on mtDNA inheritance. In 2010, Dr Xu joined the National Institutes of Health as a Principal Investigator and was promoted to Senior Investigator in 2017. His research program at NIH focuses on understanding the fundamental principles and cellular mechanisms governing mtDNA transmission.

Mara Zilocchi, PhD, University of Milano-Bicocca, Italy

Dr Mara Zilocchi's scientific career began at the end of 2014, when she started her PhD at the University of Insubria, Italy. In 2019, Dr Zilocchi was employed as a postdoctoral fellow at the University of Regina, Canada, where she was involved in several systems neuroscience-related projects, including the development of a co-fractionation/mass spectrometry approach and a bioinformatic pipeline for investigating mitochondrial protein assemblies in neuronal cells. Since 2023, Dr Zilocchi have been employed at the University of Milano-Bicocca, Italy, as an Assistant Professor, where she is currently studying nuclear-mitochondrial crosstalk changes in amyotrophic lateral sclerosis. Her research has always been focused on deciphering mitochondrial dysfunctions in neurodegenerative and neuropsychiatric disorders, using both -omics and targeted approaches.

About the Collection

BMC Biology is calling for submissions to our Collection on Mitochondrial metabolism and dynamics.  Mitochondria play a pivotal role in cellular metabolism, energy production, and cell signaling. Understanding the intricate mechanisms of mitochondrial metabolism and dynamics is crucial for unraveling the cellular responses to numerous stressors in animals and plants, as well as the pathophysiology of diverse diseases and adaptation to environmental changes at organismal levels.

We welcome submissions that explore the molecular mechanisms underlying mitochondrial function, mitochondrial dynamics, and their involvement in metabolic diseases, neurodegenerative disorders, and cancer. We further invite submissions that provide insights into potential therapeutic targets and interventions for diseases associated with mitochondrial dysfunction. This Collection also encourages research aiming to understand the function of mitochondria in plants and their role in physiological and adaptive responses to biotic and abiotic stress.

Topics may include, but are not limited to:

  • Study of mitochondrial DNA mutations and their effects on metabolism, disease and environmental adaptation
  • Interaction between nuclear and mitochondrial genomes
  • Mechanisms of ATP production and energy conversion in mitochondria
  • Impact of oxidative stress on mitochondrial and cellular function
  • Factors regulating mitochondrial biogenesis
  • Role of mitochondria in cellular signaling, including apoptosis and metabolic signaling
  • Molecular mechanisms of mitochondrial fission and fusion
  • Mechanisms and regulation of mitophagy and its role in health and disease
  • Mitochondrial dysfunction in metabolic diseases, neurodegenerative diseases, and cancer
  • Animal and plant models of mitochondrial dysfunction
  • Therapeutic approaches targeting mitochondrial pathways
  • Role of mitochondrial function in environmental adaptation


This Collection supports and amplifies research related to SDG 3: Good Health and Well-Being and SDG 15: Life on Land.

All manuscripts submitted to this journal, including those submitted to collections and special issues, are assessed in line with our editorial policies and the journal’s peer review process. Reviewers and editors are required to declare competing interests and can be excluded from the peer review process if a competing interest exists.

Image credit: © Dr_Microbe / Stock.adobe.com

There are currently no articles in this collection.

Submission Guidelines

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This Collection welcomes submission of original Research and Methodology Articles. Should you wish to submit a different article type, please read our submission guidelines to confirm that type is accepted by the journal. Articles for this Collection should be submitted via our submission system, Snapp. During the submission process you will be asked whether you are submitting to a Collection, please select "Mitochondrial metabolism and dynamics" from the dropdown menu.

All manuscripts submitted to this journal, including those submitted to collections and special issues, are assessed in line with our editorial policies and the journal’s peer review process. Reviewers and editors are required to declare competing interests and can be excluded from the peer review process if a competing interest exists.