BMC Medical Genomics is calling for submissions to our Collection on Tumor microenvironment in cancer genomics. The tumor microenvironment (TME) plays a critical role in the survival, progression, and treatment response of various cancers. It encompasses a complex network of cells, extracellular matrix components, and signaling molecules that interact dynamically with tumor cells. Understanding the TME is essential for deciphering the mechanisms underlying tumorigenesis, metastasis, and therapeutic resistance. Recent advances in cancer genomics have provided valuable insights into how genomic alterations within tumor cells are influenced by their surrounding microenvironment, paving the way for a deeper understanding of cancer biology. Advances in single-cell genomics, and spatial transcriptomics have revolutionized our ability to characterize the cellular composition and functional states within the TME. These technologies enable researchers to pinpoint specific cellular interactions, and signaling pathways linked to treatment resistance, aiding in the design of targeted therapies that can effectively disrupt these processes.
This Collection aims to gather innovative research exploring the TME in the context of cancer genomics. We invite submissions that investigate the interactions between TME and genomic alterations, implications for drug delivery, and the mechanisms underlying treatment resistance.
All manuscripts submitted to this journal, including those submitted to collections and special issues, are assessed in line with our editorial policies and the journal’s peer review process. Reviewers and editors are required to declare competing interests and can be excluded from the peer review process if a competing interest exists.
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