João Pedro Alves Lopes, PhD, Karolinska Institutet & Karolinska University Hospital, Sweden
Soumita Das, PhD, University of Massachusetts-Lowell, USA
Michael Sigal, PhD, Charité Universitätsmedizin Berlin & Max Delbrück Center for Molecular Medicine, Germany
João Pedro Alves Lopes, PhD, Department of Women's and Children's Health, Karolinska Institutet and Karolinska University Hospital, Sweden
Soumita Das, PhD, Department of Biomedical and Nutritional Science, University of Massachusetts-Lowell, USA
Michael Sigal, PhD, Charité Universitätsmedizin Berlin & Max Delbrück Center for Molecular Medicine, Germany
Studies can be based on organoids derived from either induced pluripotent stem cells or tissue-derived cells (embryonic or adult stem cells or progenitor or differentiated cells from healthy or diseased tissues, such as tumors).
We welcome submissions focusing on studies investigating the mechanisms of self-organization and cellular differentiation within organoids, and how these processes recapitulate human tissue architecture and pathology. We are especially interested in studies addressing the issues of improving tissue patterning, specialization, and function, and avoiding tumorigenicity after transplantation of organoids. We will also consider studies that demonstrate the application of organoids in personalized medicine, such as drug screening, toxicity testing, and the identification of novel therapeutic targets.
We are interested in studies focusing on the refinement of methods to enhance the fidelity and functional maturity of organoids, especially those integrating organoid models with cutting-edge technologies such as advanced imaging, single-cell and spatial omics, microfluidic chip systems and bioprinting.
This Collection supports and amplifies research related to SDG 3: Good Health and Well-Being.
All manuscripts submitted to this journal, including those submitted to collections and special issues, are assessed in line with our editorial policies and the journal’s peer review process. Reviewers and editors are required to declare competing interests and can be excluded from the peer review process if a competing interest exists.
Image credit: Tocci & Sayed et al, Das Lab, UMass-Lowell
There are currently no articles in this collection.
This Collection welcomes submission of original Research and Methodology Articles. Should you wish to submit a different article type, please read our submission guidelines to confirm that type is accepted by the journal. Articles for this Collection should be submitted via our submission system, Snapp. During the submission process you will be asked whether you are submitting to a Collection, please select "Organoids: advancements in normal development and disease modeling, and Regenerative Medicine" from the dropdown menu.
All manuscripts submitted to this journal, including those submitted to collections and special issues, are assessed in line with our editorial policies and the journal’s peer review process. Reviewers and editors are required to declare competing interests and can be excluded from the peer review process if a competing interest exists.