Guest edited by Naoki Hosen, Osaka University, Japan
A thematic series in Inflammation and Regeneration.
This series of articles has not been sponsored. All articles have undergone the journal's standard peer review process overseen by the Guest Editor. The Guest Editor declares no competing interests.
Designer immune cells
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Citation: Inflammation and Regeneration 2024 44:48
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Genome editing iPSC to purposing enhancement of induce CD8 killer T cell function for regenerative immunotherapy
In recent years, immunotherapy has become a standard cancer therapy, joining surgery, chemotherapy, and radiation therapy. This therapeutic approach involves the use of patient-derived antigen-specific T cells or...
Citation: Inflammation and Regeneration 2024 44:20 -
Hippo pathway in cell–cell communication: emerging roles in development and regeneration
The Hippo pathway is a central regulator of tissue growth that has been widely studied in mammalian organ development, regeneration, and cancer biology. Although previous studies have convincingly revealed its...
Citation: Inflammation and Regeneration 2024 44:18 -
Identification of cancer-specific cell surface targets for CAR-T cell therapy
One should identify appropriate cell surface targets to develop new CAR-T cells. Currently, lineage-specific antigens such as CD19 or B cell maturation antigen (BCMA) are being used as targets for CAR-T cells....
Citation: Inflammation and Regeneration 2024 44:17 -
Designer cell therapy for tissue regeneration
Cancer cell therapy, particularly chimeric antigen receptor (CAR) T-cell therapy for blood cancers, has emerged as a powerful new modality for cancer treatment. Therapeutic cells differ significantly from conv...
Citation: Inflammation and Regeneration 2024 44:15 -
Gene editing technology to improve antitumor T-cell functions in adoptive immunotherapy
Adoptive immunotherapy, in which tumor-reactive T cells are prepared in vitro for adoptive transfer to the patient, can induce an objective clinical response in specific types of cancer. In particular, chimeri...
Citation: Inflammation and Regeneration 2024 44:13