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Fibrotic diseases: from models to therapies

Edited by:

Professor Nai-Chen Cheng, MD, PhD, National Taiwan University Hospital, Taiwan

Submission Status: Open   |   Submission Deadline: 3 November 2025


Stem Cell Research & Therapy is calling for submissions to our Collection on fibrotic diseases, with a focus on novel cell-based therapies, targeted molecular interventions, and personalized medicine approaches.

Image credit: © [M] pinkeyes / stock.adobe.com

About the Collection

Fibrosis, characterized by excessive connective tissue formation, poses a major challenge in various conditions, including liver cirrhosis, pulmonary fibrosis, and cutaneous scar. Recent advances have illuminated the potential of in-vitro models and 3D tissue engineering to better mimic the fibrotic environment, paving the way for innovative therapies aimed at promoting scarless wound healing and tissue regeneration.
The exploration of molecular mechanism in the context of fibrosis has led to promising breakthroughs, such as the identification of specific stem cell populations that can modulate fibrotic responses and enhance tissue repair. Furthermore, the development of advanced in-vitro models has allowed researchers to study the cellular and molecular mechanisms underlying fibrosis in a controlled environment, facilitating drug screening and the evaluation of therapeutic strategies. As we continue to deepen our understanding of these complex processes, we can anticipate future advances that may include novel cell-based therapies, targeted molecular interventions, and personalized medicine approaches that address the unique fibrotic profiles of individual patients.
We invite researchers to contribute to this Collection by submitting original research and review articles. Topics of interest include but are not limited to: 

  • Mechanisms of fibrosis
  • Stem cell therapy for fibrosis
  • In-vitro models of fibrotic diseases
  • 3D models in fibrosis research
  • Wound healing and fibrosis
  • Therapeutic strategies for fibrosis
  • Biomarkers of fibrotic diseases
  • Clinical applications of cell therapy.

Meet the Guest Editor

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Professor Nai-Chen Cheng, MD, PhD, National Taiwan University Hospital, Taiwan

Dr. Cheng is a board-certified plastic surgeon in Taiwan. His research has been focused on wound infection and applying stem cells for regenerative wound healing. His work has been published in several first-tier journals. Dr. Cheng has received many international and domestic awards in recognition of his excellent track record in the research and clinical work, and he has been invited to give a speech in several renowned institutes and international conferences. He has also received multiple funding for his research projects from both the governmental and business sectors. In 2021, Dr. Cheng was elected as the president of Taiwan Society for Wound Care.

 


There are currently no articles in this collection.

Submission Guidelines

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This Collection welcomes submission of original research and review articles. Should you wish to submit a different article type, please read our submission-guidelines to confirm that type is accepted by the journal. 

Articles for this Collection should be submitted via our submission system, Editorial Manager. Please select the appropriate Collection title “Fibrotic diseases: from models to therapies" from the dropdown menu.

Articles will undergo the journal’s standard peer-review process and are subject to all the journal’s standard policies. Articles will be added to the Collection as they are published.

The Editors have no competing interests with the submissions which they handle through the peer-review process. The peer-review of any submissions for which the Editors have competing interests is handled by another Editorial Board Member who has no competing interests.