Guest Editors:
Kristopher T Kahle, MD, PhD, Massachusetts General Hospital, Boston, United States of America
Ville Leinonen, MD, PhD, Kuopio University Hospital, Finland
This collection is no longer accepting submissions.
Fluids and Barriers of the CNS is calling for submissions to our Collection on Genetic Aspects of Hydrocephalus.
Heterozygous CWH43 loss-of-function (LOF) variants have been identified as iNPH risk factors, with 10–15% of iNPH patients carrying these variants in cohorts from the US. Mouse model harboring CWH43 LOF variants ...
AQP4 is expressed in the endfeet membranes of subpial and perivascular astrocytes and in the ependymal cells that line the ventricular system. The sporadic appearance of obstructive congenital hydrocephalus (O...
Hydrocephalus (HC) is a heterogenous disease characterized by alterations in cerebrospinal fluid (CSF) dynamics that may cause increased intracranial pressure. HC is a component of a wide array of genetic synd...
Patients with idiopathic normal-pressure hydrocephalus (iNPH) are predisposed to developing dementing disorders. Cerebrospinal fluid (CSF) shunt implantation is a treatment used to improve the motor and cognit...
Hydrocephalus constitutes a complex neurological condition of heterogeneous origin characterized by excessive cerebrospinal fluid (CSF) accumulation within the brain ventricles. The condition may dangerously e...
This new Collection from Fluids and Barriers of the CNS seeks to publish new research and reviews on genetic aspects of hydrocephalus. That includes both human genetic studies seeking to identify new genetic causes of hydrocephalus and animal studies using genetic manipulations to provide insight into the role of specific proteins/pathways in regulating CSF dynamics and hydrocephalus development. Studies on the role of epigenetics in hydrocephalus are also most welcome.
Before submitting your manuscript, please ensure you have read our submission guidelines. Articles for this Collection should be submitted via our submission system, Snapp. During the submission process you will be asked whether you are submitting to a Collection, please select "Genetic Aspects of Hydrocephalus" from the dropdown menu.
Articles will undergo the journal’s standard peer-review process and are subject to all of the journal’s standard policies. Articles will be added to the Collection as they are published.
The Guest Editors have no competing interests with the submissions which they handle through the peer review process. The peer review of any submissions for which the Guest Editors have competing interests is handled by another Editorial Board Member who has no competing interests.
