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Call for papers - In vitro models for biocompatibility testing

Guest Editors

Stéphane Durual, PhD (PD), University of Geneva, Switzerland 
Laurine Marger, PhD, University of Geneva, Switzerland 
Carlos Miguel Marto, DMD, University of Coimbra, Portugal
Thanaphum Osathanon, DDS, PhD, Chulalongkorn University, Thailand 

Submission Status: Open   |   Submission Deadline: 3 October 2025

BMC Oral Health invites researchers to contribute to its new Collection, In vitro models for biocompatibility testing. We welcome submissions that explore cell culture techniques, 3D models, and tissue engineering applications, aiming to enhance our understanding of material interactions and their implications for restorative dentistry. Through this Collection, we seek to advance the field and improve patient safety and outcomes in dental care.


New Content ItemThis Collection supports and amplifies research related to SDG 3: Good Health and Well-being.

Meet the Guest Editors

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Stéphane Durual, PhD (PD), University of Geneva, Switzerland

Dr Stéphane Durual completed his studies at the Université Claude Bernard Lyon 1 in France. Following the completion of an undergraduate program in biochemistry, he proceeded to undertake doctoral studies in human biology, earning the degree of Doctor of Science in 2003. In 2004, he joined the University of Geneva. Dr Durual initiated research lines to optimize the surfaces of endo-osseous implants and develop and characterize bone substitutes. Currently, his work is oriented towards regenerative medicine, with one of the group's principal projects focusing on the 3D printing of pre-vascularized hard tissues and soft tissues. 

Laurine Marger, PhD, University of Geneva, Switzerland 

Dr Laurine Marger undertook studies in neurobiology at the University of Montpellier, France. During her doctoral studies in neurobiology, she investigated the role of ion channels in cardiac rhythm, obtaining her Doctor of Science degree in 2008. She then proceeded to undertake a four-year postdoctoral fellowship at the Montreal Heart Institute. Following a period of several years in the private sector, Dr Marger joined the University of Geneva in 2017. Her research interests include bone regeneration and the development of osteogenic niches. Her current research project is concerned with the use of 3D printing and the development of microbiological tests to characterize different bioactive implant coatings. 

Carlos Miguel Marto, DMD, University of Coimbra, Portugal

Dr Carlos Miguel Marto holds a master’s degree in Dentistry from the Faculty of Medicine at the University of Coimbra, Portugal, followed by postgraduate studies in Biomedical Research and Health Sciences. Currently, he serves as a teaching fellow at the Faculty of Medicine, University of Coimbra, and a researcher at the Centre for Innovative Biomedicine and Biotechnology and the Centre for Mechanical Engineering, Materials and Processes. His research focuses on experimental pathology, in vitro and animal models, tissue regeneration—particularly involving biomaterials and stem-like cells—as well as the cytotoxicity and biocompatibility evaluation of dental biomaterials.

Thanaphum Osathanon, DDS, PhD, Chulalongkorn University, Thailand

Dr Thanaphum Osathanon earned his bachelor’s in dental surgery from Chulalongkorn University He continued his studies and earned a Doctor of Philosophy in oral biology from the University of Washington, USA. Currently, Dr Osathanon is an Associate Dean of Academic Affairs and Graduate Studies, and is the Program Director in Oral Biology, Faculty of Dentistry, at Chulalongkorn University. He has been published on more than 150 occasions and serves as an editorial board member of BMC Oral Health.

About the Collection

BMC Oral Health is pleased to announce our upcoming Collection on In vitro models for biocompatibility testing. Evaluating biocompatibility is a critical aspect of developing dental materials, as it ensures that these materials do not elicit adverse biological responses when used in clinical applications. In vitro models, including cell culture and tissue engineering approaches, have emerged as essential tools for assessing the compatibility of dental materials with human tissues, particularly in restorative dentistry. These models allow researchers to simulate the oral environment, providing insights into the interactions between dental materials and biological systems, which is crucial for the safe and effective use of these materials in dental practice.

As research grows, we can anticipate the development of more sophisticated in vitro models that closely mimic the complex architecture and functionality of oral tissues. Future advances may include the use of organ-on-a-chip technologies and bioengineered tissues, which could provide even more reliable data on the biocompatibility of dental materials. These developments will not only enhance our understanding of material interactions but also facilitate the design of safer and more effective dental products.

We invite submissions on a range of topics that include but are not limited to:

  • Biocompatibility of dental materials
  • 3D models in dental research
  • Cell culture techniques for toxicity testing
  • Tissue engineering applications in restorative dentistry
  •  Assessing dental pulp responses to materials


This Collection supports and amplifies research related to SDG 3: Good Health and Well-being.

All manuscripts submitted to this journal, including those submitted to collections and special issues, are assessed in line with our editorial policies and the journal’s peer review process. Reviewers and editors are required to declare competing interests and can be excluded from the peer review process if a competing interest exists.

Image credit: © nicolas_/ stock.adobe.com

  1. The success of root canal treatment and regenerative endodontics relies on thorough disinfection and dentin integrity preservation to ensure long-term tooth survival. This study evaluates the pH stability, mat...

    Authors: Rathna Piriyanga, Manish Ranjan, Anand Sherwood, Mohammad Fareed and Mohmed Isaqali Karobari
    Citation: BMC Oral Health 2025 25:461
    Content type: Research Published on:

Submission Guidelines

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This Collection welcomes submission of original Research Articles. Should you wish to submit a different article type, please read our submission guidelines to confirm that type is accepted by the journal. Articles for this Collection should be submitted via our submission system, Snapp. During the submission process you will be asked whether you are submitting to a Collection, please select In vitro models for biocompatibility testing from the dropdown menu.

All manuscripts submitted to this journal, including those submitted to collections and special issues, are assessed in line with our editorial policies and the journal’s peer review process. Reviewers and editors are required to declare competing interests and can be excluded from the peer review process if a competing interest exists.