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Call for papers - Microbial cell bioprocessing and biomanufacturing

Guest Editors

Vivek Kumar Gaur, PhD, Ulsan National Institute of Science and Technology, South Korea
Alok Patel, PhD, Luleå University of Technology, Sweden
Pratyoosh Shukla, PhD, DSc, FNAAS, FBRS, FAMSc, Banaras Hindu University, India

Submission Status: Open   |   Submission Deadline: 30 June 2025

BMC Biotechnology welcomes submissions to the collection, Microbial cell bioprocessing and biomanufacturing. The collection aims to cover biotechnological research and applications emerging on microbial bioprocessing and biomanufacturing. We invite submissions on topics such as microbial metabolic engineering, cell factory optimization, recombinant protein production, sustainable bioproduction of valuable metabolites using microorganisms, biomass utilization, integration of systems and synthetic biology to engineer microbial cell factories, microbial immobilization, bioprocess innovations, microbial consortia, and industrial applications of microbial bioprocessing.


New Content ItemThis Collection supports and amplifies research related to SDG 9: Industry, Innovation & Infrastructure

Meet the Guest Editors

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Vivek Kumar Gaur, PhD, Ulsan National Institute of Science and Technology (UNIST), South Korea

Dr Gaur is currently a Research Assistant Professor in the School of Energy and Chemical Engineering at the Ulsan National Institute of Science and Technology (South Korea). His primary research areas include environmental biotechnology, metabolic engineering, and bioprocess engineering. Dr Gaur has authored over 100 publications, including research and review papers, book chapters, and conference communications, and holds three patents. He has received several awards, notably the APJ Abdul Kalam Best PhD thesis award from the International Society for Energy, Environment, and Sustainability, and the young researcher award for his work on microbial biosurfactants.

Alok Patel, PhD, Luleå University of Technology, Sweden

Dr Patel is an Assistant Professor in Biochemical Process Engineering at the Department of Civil, Environmental, and Natural Resources Engineering at Luleå University of Technology (Sweden). He began his notable career in bioprocess engineering with a PhD from the Department of Biosciences and Bioengineering at IIT Roorkee (India). Dr Patel has since embarked on an independent research career within the Biochemical Process Engineering (BPE) group at LTU. He leads efforts in developing a microalgal-based biorefinery in his division and serves as the principal investigator for research grants funded by the Swedish Research Council Formas. He also co-leads several projects funded by prestigious institutions such as EU Horizon and various national agencies. His academic achievements include over 90 publications and three edited books. Additionally, he contributes to the academic community as an Associate Editor and an esteemed editorial board member for several peer-reviewed journals, including BMC Biotechnology.

Pratyoosh Shukla, PhD, DSc, FNAAS, FBRS, FAMSc, Banaras Hindu University, India

Dr Shukla is currently a Professor and Coordinator at the School of Biotechnology, Banaras Hindu University (India). His research focuses on enzyme technology and protein bioinformatics. Prof. Shukla has authored over 230 publications in SCI journals, 9 books, and 40 book chapters. He has led over 15 research and development projects funded by national and international agencies as principal investigator (PI) or Co-PI. Dr Shukla is a Fellow of the National Academy of Agricultural Sciences (FNAAS), the Association of Microbiologists of India (FAMI/FAMSc), and the Biotech Research Society of India (FBRS). He has received numerous awards, including the ASM-Indo-USA Visiting Professor Award, recognition as one of the Top 10 Best Researchers of India, the AMI-Alembic Award in Industrial Microbiology, the BHU Most Productive Researcher Award (2022), and the Faculty Research Award (2023).

About the Collection

Microbial cell factories are engineered microorganisms that harbor metabolic pathways for the sustainable production of chemicals of interest, including pharmaceuticals, antibodies and recombinant proteins, as well as biofuels and other industrial products. Microbial cell bioprocessing and biomanufacturing involve the use of microbial cell factories and advanced bioprocesses, alongside the microbial metabolic engineering to enhance the production of valuable compounds, followed by their purification and characterization. Using microbial cell factories for the sustainable bioproduction of chemicals is becoming increasingly relevant as it can provide shorter production cycles and higher production yield relative to chemical synthesis or plant extraction methods. Ongoing research in this rapidly expanding field promises significant advances for instance in integrating systems biology, synthetic biology and metabolic engineering to optimize microbial cell factories and design novel metabolic pathways, discovering and producing new industrially-relevant natural compounds, and developing sustainable and efficient bioprocessing technologies that adhere to green chemistry and circular economy principles.

In support of the UN Sustainable Development Goal 9 (SDG 9; Industry, Innovation, and Infrastructure), BMC Biotechnology welcomes submissions to the collection, Microbial cell bioprocessing and biomanufacturing. The collection aims to cover biotechnological research and applications emerging on microbial bioprocessing and biomanufacturing. We invite researchers and experts in the field to submit research articles that explore, but are not limited to, the following topics:

  • Microbial metabolic engineering
  • Optimization of microbial cell factories and microbial bioprocesses
  • Production and bioprocessing of recombinant proteins, metabolites and natural compounds using microbial cell factories
  • Sustainable production of valuable metabolites and natural compounds using microorganisms
  • Biomass and feedstocks utilization for bioenergy and bioproducts
  • Systems biology, synthetic biology and directed evolution approaches applied to engineer microbial cell factories
  • Immobilization of microbial cells and their biotechnological applications
  • Machine learning and artificial intelligence-aided design of novel biosynthetic pathways for the production of chemicals using microbial cells
  • Machine learning and artificial intelligence-aided bioprocess optimization
  • Robotics in bio-manufacturing
  • Innovations in bioprocess integration and intensification
  • Microbial consortia and co-cultures in bioprocessing
  • Industrial applications of microbial bioprocessing
  • Environmental impact assessments of microbial biomanufacturing processes


Image credit: © Reptile8488 / Getty Images / iStock

  1. In this study, the biological activities of Otidea onotica were investigated using two optimization methods, Response Surface Methodology (RSM) and Artificial Neural Network-Genetic Algorithm (ANN-GA). The extrac...

    Authors: Mustafa Sevindik, Celal Bal, Tetiana Krupodorova, Ayşenur Gürgen and Emre Cem Eraslan
    Citation: BMC Biotechnology 2025 25:25
    Content type: Research Published on:

  2. Natural colorants produced by the cyanobacterium include carotenoids, chlorophyll a and phycocyanin. The current study used the Synechocystis sp. PCC 6803 to examine how abiotic stress conditions, such as low tem...

    Authors: Namrata Bhagat, Guddu Kumar Gupta, Amritpreet Kaur Minhas, Deepak Chhabra and Pratyoosh Shukla
    Citation: BMC Biotechnology 2025 25:23
    Content type: Research Published on:

  3. Proteases are essential in various industries due to their unique substrate specificities and robustness in different operational conditions. Bacillus strains consist of a genotype favorable for rapid growth whil...

    Authors: Stefan Kittler, Fabian Müller, Mohamed Elshazly, Georg Benjamin Wandrey, Tobias Klein, Andreas Daub, Oliver Spadiut and Julian Kopp
    Citation: BMC Biotechnology 2025 25:13
    Content type: Research Published on:

  4. Biohydrogen production from agro-industrial wastes through dark fermentation offers several advantages including eco-friendliness, sustainability, and the simplicity of the process. This study aimed to produce...

    Authors: Norhan Elerakey, Abdel-Hamied M. Rasmey, Akram A. Aboseidah and Heba Hawary
    Citation: BMC Biotechnology 2024 24:105
    Content type: Research Published on:

  5. The laccase Lcc9 from Coprinopsis cinerea has optimal catalytic activity at moderate to alkaline pH conditions, making it invaluable for industrial applications. However, C. cinerea naturally secretes Lcc9 at low...

    Authors: Dongbang Yao, Xiaozhuang Liu, Hui Wang, Juanjuan Liu, Zemin Fang and Yazhong Xiao
    Citation: BMC Biotechnology 2024 24:95
    Content type: Research Published on:

  6. Vitamin B12 is a crucial B-group vitamin, first isolated from the liver due to its role in combating pernicious anemia. It is distinguished by its unique and complex structure, which makes its chemical synthesis ...

    Authors: Rania M. M. Abdel-Baki, Marwa N. Ahmed, Olfat S. Barakat and Galal M. Khalafalla
    Citation: BMC Biotechnology 2024 24:90
    Content type: Research Published on:

  7. The encapsulation of metagenome-derived multi-enzymes presents a novel approach to improving poultry feed by enhancing nutrient availability and reducing anti-nutritional factors. By integrating and encapsulat...

    Authors: Shohreh Ariaeenejad, Mehrshad Zeinalabedini, Akram Sadeghi, Sajjad Gharaghani and Mohsen Mardi
    Citation: BMC Biotechnology 2024 24:76
    Content type: Research Published on:

Submission Guidelines

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This Collection welcomes submission of original Research Articles. Should you wish to submit a different article type, please read our submission guidelines to confirm that type is accepted by the journal. Articles for this Collection should be submitted via our submission system, Snapp. During the submission process you will be asked whether you are submitting to a Collection, please select "Microbial cell bioprocessing and biomanufacturing" from the dropdown menu.

Articles will undergo the journal’s standard peer-review process and are subject to all of the journal’s standard policies. Articles will be added to the Collection as they are published.

The Editors have no competing interests with the submissions which they handle through the peer review process. The peer review of any submissions for which the Editors have competing interests is handled by another Editorial Board Member who has no competing interests.