Mitochondria function in infection and immunity

Guest Editors

Rudranil De, PhD, Amity Institute of Biotechnology, Amity University Kolkata, India
Nicholas M. Maurice, MD, Emory University School of Medicine, USA

Close up of the mitochondria BMC Immunology has published this Collection on Mitochondria function in infection and immunity. Mitochondria, once solely recognized as the cell's powerhouse, now play pivotal roles in immune responses and infectious diseases. This Collection compiles cutting-edge research exploring the multifaceted roles of mitochondria in innate immunity, inflammation, and their implications for various diseases. Submissions covering diverse topics, including mitochondrial dynamics in immune cells, signaling pathways in inflammation, pathogen recognition, host defense mechanisms, crosstalk with innate immunity, mitochondrial involvement in disease states, and therapeutic targeting, were encouraged.

New Content Item This Collection supports and amplifies research related to SDG 3: Good Health and Wellbeing.

Meet the Guest Editors

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Rudranil De, PhD, Amity Institute of Biotechnology, Amity University, India

potrait of guest editor rudranil de Dr Rudranil De has a PhD in Biochemistry and has more than five years of independent research experience in cancer cell biology and immuno-oncology. His work focuses on investigating mitochondrial dynamics, bioenergetics, and metabolism in cancer. Additionally, he studies inflammatory signaling in cancer progression and immune infiltration within the tumor microenvironment. Dr De's current research interest lies in exploring metabolic regulations in tumor-associated macrophages, dendritic cells, and NK cells, specifically in the context of gastric and head and neck cancer. His research findings have been published in several international peer-reviewed journals.

Nicholas M. Maurice, MD, Emory University School of Medicine, USA

Portrait photo of physician scientist Nicholas Maurice Nicholas Maurice, MD, is an Assistant Professor of Medicine in the Department of Medicine, Division of Pulmonary, Allergy, Critical Care, and Sleep Medicine at Emory University School of Medicine and at the Atlanta VA Health Care System. He is a physician-scientist with a basic and translational science research program that aims to uncover a deeper understanding of the host response to bacterial pneumonia. He investigates the effects of bacterial pathogens on host cell mitochondrial processes and how these modulations may affect the innate immune response. His current focus aims to reveal the role of mitochondrial DNA damage and repair in the epithelial host response to Streptococcus pneumoniae.

About the Collection

BMC Immunology has published this Collection on Mitochondria function in infection and immunity. Mitochondria, once regarded solely as the powerhouse of the cell, have emerged as pivotal players in immune responses and infectious diseases. This Collection compiles cutting-edge research exploring the multifaceted roles of mitochondria in innate immunity, inflammation, and their implications for various diseases.

We welcomed submissions covering a broad range of topics. Areas of interest include, but were not limited to:

Mitochondrial dynamics and function in immune cells: investigating how mitochondria contribute to the functionality of immune cells in the context of infection and immunity
Mitochondrial signaling pathways in inflammation: exploring the intricate signaling networks within mitochondria that modulate inflammatory responses
Mitochondrial involvement in pathogen recognition: understanding how mitochondria contribute to the detection of pathogens and the initiation of immune responses
Mitochondria-mediated host defense mechanisms: examining the role of mitochondria in the clearance and destruction of pathogens during innate immune responses
Crosstalk between mitochondria and innate immunity: investigating the dynamic interactions between mitochondrial function and innate immune pathways
Mitochondria in disease states: exploring the impact of dysfunctional mitochondrial processes on diseases, including infectious diseases, autoimmune diseases, chronic inflammatory conditions, and cancer
Therapeutic targeting of mitochondrial function: presenting novel therapeutic approaches that leverage mitochondria to treat infectious and inflammatory diseases

This Collection aligns with Sustainable Development Goal (SDG) 3: Good Health and Wellbeing, contributing to the understanding of mitochondrial involvement in infection and immunity. Researchers in this field play a crucial role in developing strategies for disease prevention, diagnosis, and treatment, ultimately promoting better health outcomes for individuals and communities.

There are currently no articles in this collection.

Submission Guidelines

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This Collection welcomes submission of original Research Articles. Should you wish to submit a different article type, please read our submission guidelines to confirm that type is accepted by the journal. Articles for this Collection should be submitted via our submission system, Snapp. During the submission process you will be asked whether you are submitting to a Collection, please select Mitochondria function in infection and immunity from the dropdown menu.

Articles will undergo the journal’s standard peer-review process and are subject to all of the journal’s standard policies. Articles will be added to the Collection as they are published.

The Editors have no competing interests with the submissions which they handle through the peer review process. The peer review of any submissions for which the Editors have competing interests is handled by another Editorial Board Member who has no competing interests.