Edited by:
Joshua Rubin, MD, PhD, Washington University, United States of America
Biology of Sex Differences is calling for submissions to our Collection on Sex/Gender Differences in Cancer.
Accumulating evidence indicates that the dysbiosis of gastrointestinal microbiota is associated with the development of gastric carcinogenesis. However, the sex-specific traits of gastrointestinal microbiota a...
DNA methylation (DNAm) influences both sex differences and cancer development, yet the mechanisms connecting these factors remain unclear.
Lung adenocarcinoma (LUAD) has been observed to have significant sex differences in incidence, prognosis, and response to therapy. However, the molecular mechanisms responsible for these disparities have not b...
Sexual dimorphism significantly influences cancer incidence and prognosis. Notably, females exhibit a lower risk and favorable prognosis for non-reproductive cancers compared to males, a pattern observable bey...
Glioblastoma (GBM) is the most common and lethal primary brain tumor in adults, with limited treatment modalities and poor prognosis. Recent studies have highlighted the importance of considering sex differenc...
Sex and age associated differences in the tumor immune microenvironment of non-muscle invasive bladder (NMIBC) cancer and associated clinical outcomes are emerging indicators of treatment outcomes. The inciden...
Lung adenocarcinoma (LUAD) is one of the most important subtypes of lung cancer. Compared with male LUAD patients, female patients have a higher incidence, but better long-term survival rate, with unknown reas...
As in other types of cancers, sex is an essential factor in the origin and progression of glioblastomas. Research in the field of endocrinology and cancer suggests that gonadal steroid hormones play an importa...
The mortality of nasopharyngeal carcinoma (NPC) is usually lower in females than in males, but the underlying mechanism remains largely unknown. We sought to describe the age-dependent patterns of gender dispa...
Males < 40 years old are more likely to be diagnosed with and die from osteosarcoma (OS). The underlying mechanisms may depend on sex differences in immune response.
Biology of Sex Differences invites authors to submit articles addressing the mechanisms underlying sex/gender differences in cancer incidence, treatment response, and survival. Topics may include, but are not limited to, mechanisms of cancer initiation and progression, epigenetics, tumor microenvironment, cancer immunology, angiogenesis, cancer metabolism, treatment response, health care access. Gender investigations should address gender as a contributing factor, not as a proxy for sex.
Before submitting your manuscript, please ensure you have read our submission guidelines. Articles for this Collection should be submitted via the submission system. During the submission process you will be asked whether you are submitting to a Collection/Thematic Series, please select "Sex/Gender Differences in Cancer" from the dropdown menu.
Articles will undergo the journal’s standard peer-review process and are subject to all of the journal’s standard policies. Articles will be added to the Collection as they are published.
The Guest Editors have no competing interests with the submissions which they handle through the peer review process. The peer review of any submissions for which the Guest Editors have competing interests is handled by another Editorial Board Member who has no competing interests.